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Sleep fragmentation and sleep-disordered breathing in individuals living close to main roads : results from a population-based study
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID 2420091
Author(s) Gerbase, M W; Dratva, J; Germond, M; Tschopp, J M; Pépin, J L; Carballo, D; Künzli, N; Probst-Hensch, N M; Adam, M; Zemp Stutz, E; Roche, F; Rochat, T
Author(s) at UniBasel Probst Hensch, Nicole
Künzli, Nino
Adam, Martin
Zemp Stutz, Elisabeth
Dratva, Julia
Year 2014
Title Sleep fragmentation and sleep-disordered breathing in individuals living close to main roads : results from a population-based study
Journal Sleep medicine
Volume 15
Number 3
Pages / Article-Number 322-8
Keywords Traffic noise, Sleep fragmentation, Sleep-disordered breathing, Heart rate variability, Gender, Cohort studies

Nighttime traffic noise is associated with sleep disturbances, but sleep fragmentation and sleep-disordered breathing (SDB) have not been demonstrated in individuals living near busy roads.; We asked 1383 participants to answer a health questionnaire and to undergo 24-h electrocardiogram (ECG). Nocturnal ECG records were used to calculate the very low frequency index (VLFI) interval, a surrogate marker of sleep fragmentation. Distances of participants' addresses to roadways were calculated using the VECTOR25© Swisstopo roads classification, a traffic noise proxy. Distances of homes within 100 or 50m of major roads defined proximity to busy roads. Adjusted multivariate logistic regressions analyzed associations between the distance of home to main roads and VLFI or self-reported SDB.; Distance of participants' homes to main roads was significantly associated with the VLFI in women (odds ratio [OR], 1.58 [confidence interval {CI}, 1.03-2.42]; P=.038) but not in men (OR, 1.35 [CI, 0.77-2.35]; P=.295). Women under hormonal replacement therapy (HRT) were at higher risk for increased VLFI when living close to main roads (OR, 2.10 [CI, 1.20-3.68]; P=.01) than untreated women (P=.584). Associations with self-reported SDB were not statistically relevant.; In our large population, women living close to main roads were at significantly higher risk for sleep fragmentation than men. The 2-fold higher risk for menopausal women under HRT underscores the vulnerability of this group.

Publisher Elsevier
ISSN/ISBN 1389-9457
Full Text on edoc No
Digital Object Identifier DOI 10.1016/j.sleep.2013.10.014
PubMed ID
ISI-Number WOS:000332769000007
Document type (ISI) Journal Article

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