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Towards X-FEL based dynamic studies on 2D and 3D nanocrystals of membrane proteins on solid supports
Third-party funded project |
Project title |
Towards X-FEL based dynamic studies on 2D and 3D nanocrystals of membrane proteins on solid supports |
Principal Investigator(s) |
Padeste, Celestino
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Co-Investigator(s) |
Stahlberg, Henning
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Organisation / Research unit |
Departement Biozentrum / Structural Biology (Stahlberg) |
Project start |
01.03.2014 |
Probable end |
28.02.2018 |
Status |
Completed |
Abstract |
The main aim of this project is the further development of sample preparation methods for XFEL protein nano-crystallography in three ways, (1) the development of supports optimized for protein crystal preparation, (2) adaptation of a liquid handling system for minimized sample consumption, and (3) developments towards pump-probe experiments on the solid supports. The involvement of teams at University of Basel and PSI working on related topics (see below) will guarantee efficient developments and access to the key instruments, such as cleanroom facilities and (synchrotron-based) characterization methods at the PSI and liquid handling/dispensing systems at the University of Basel. Furthermore, participation at upcoming measurements at XFEL facilities will be planned.
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Financed by |
Other sources
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29/03/2024
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