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Role of the innate immune system in type 2 diabetes
Third-party funded project |
Project title |
Role of the innate immune system in type 2 diabetes |
Principal Investigator(s) |
Donath, Marc
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Organisation / Research unit |
Departement Biomedizin / Diabetes Research (Donath), Bereich Medizinische Fächer (Klinik) / Endokrinologie, Diabetologie und Metabolismus (Donath) |
Project start |
01.04.2013 |
Probable end |
31.03.2016 |
Status |
Completed |
Abstract |
Our research focuses on the mechanisms of decreased insulin production in type 2 diabetes. We have described an inflammatory process underlying the defect of insulin production in this condition. On the basis of this we conducted clinical studies. This program has now entered the phase 3 of clinical development. The objective of the present project is to uncover additional roles of the immune system in the regulation of insulin secretion during adaptation to obesity and its contribution to diabetes |
Financed by |
Swiss National Science Foundation (SNSF)
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14/05/2024
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