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APOPO's tuberculosis research agenda : achievements, challenges and prospects
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
 
ID 1634690
Author(s) Beyene, Negussie; Mahoney, Amanda; Cox, Christophe; Weetjens, Bart; Makingi, George; Mgode, Georgies; Durgin, Amy; Kuipers, Dian; Jubitana, Maureen; Egwaga, Saidi; Kamara, Deus; Lwilla, Fred; Mfinanga, Sayoki G; Kahwa, Amos; Machang'u, Robert; Kazwala, Rudovick; Reither, Klaus; Kaufmann, Stefan H E; Poling, Alan
Author(s) at UniBasel Reither, Klaus
Year 2012
Title APOPO's tuberculosis research agenda : achievements, challenges and prospects
Journal Tanzania journal of health research
Volume 14
Number 2
Pages / Article-Number 121-30
Abstract This article describes Anti-Persoonsmijnen Ontmijnende Product Ontwikkeling (APOPO) recent use of specially trained African giant pouched rats as detectors of pulmonary tuberculosis in people living in Tanzania. It summarizes the achievements and challenges encountered over the years and outlines future prospects. Since 2008, second-line screening by the rats has identified more than 2000 tuberculosis-positive patients who were missed by microscopy at Direct Observation of Treatment--Short Course centres in Tanzania. Moreover, data that are reviewed herein have been collected with respect to the rats' sensitivity and specificity in detecting tuberculosis. Findings strongly suggest that scent-detecting rats offer a quick and practical tool for detecting pulmonary tuberculosis and within the year APOPO's tuberculosis-detection project will be extended to Mozambique. As part of its local capacity building effort, APOPO hires and trains Tanzanians to play many important roles in its TB detection project and provides research and training opportunities for Tanzanian students.
Publisher HRUTF
edoc-URL http://edoc.unibas.ch/dok/A6094069
Full Text on edoc No
Digital Object Identifier DOI 10.4314/thrb.v14i2.5
PubMed ID http://www.ncbi.nlm.nih.gov/pubmed/26591733
ISI-Number MEDLINE:26591733
Document type (ISI) Journal Article
 
   

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