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An automated, interactive analysis system for ultrasound sequences of the common carotid artery
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID 1634679
Author(s) Teynor, Alexandra; Caviezel, Seraina; Dratva, Julia; Künzli, Nino; Schmidt-Trucksäss, Arno
Author(s) at UniBasel Dratva, Julia
Künzli, Nino
Year 2012
Title An automated, interactive analysis system for ultrasound sequences of the common carotid artery
Journal Ultrasound in medicine and biology : official journal of the World Federation for Ultrasound in Medicine and Biology
Volume 38
Number 8
Pages / Article-Number 1440-50
Keywords Common carotid artery, Intima media thickness, Lumen diameter, Automatic ultrasound analysis, Dual dynamic programming, Interactive system
Abstract Structural parameters of the common carotid artery (CCA) have shown to correlate with the risk of cardiovascular disease, but their precise measurement is challenging. We developed an automatic detection system with manual interaction capabilities that can reliably analyze B-mode ultrasound sequences of the CCA over several heart cycles. We evaluated 3824 frames from 40 sequences in two data qualities. Two readers measured the intima media thickness (IMT) and the lumen diameter at two evaluation times (T1/T2). A Bland-Altman analysis of the average IMT showed a bias +/- SD of 0.002 +/- 0.010 mm (T1), -0.004 +/- 0.008 mm (T2) for completely automatic detections and -0.004 +/- 0.010 mm (T1), -0.003 +/- 0.010 mm (T2) for clips with manual corrections. The combination of automated analysis and manual intervention provides precise parameters as biomarkers for the atherosclerotic process and makes the system suitable for large scale epidemiological research, diagnostic and clinical practice
Publisher Pergamon Press
ISSN/ISBN 0301-5629
Full Text on edoc No
Digital Object Identifier DOI 10.1016/j.ultrasmedbio.2012.03.015
PubMed ID
ISI-Number WOS:000306107300017
Document type (ISI) Article

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