Aldol reactions in water using a beta-cyclodextrin-binding proline derivative
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
 
ID 163276
Author(s) Liu, Kegang; Haeussinger, Daniel; Woggon, Wolf-D.
Author(s) at UniBasel Woggon, Wolf-Dietrich
Year 2007
Title Aldol reactions in water using a beta-cyclodextrin-binding proline derivative
Journal Synlett
Volume 14
Number 14
Pages / Article-Number 2298-2300
Keywords adamantane, aldol reaction, beta-cyclodextrin, proline, organocatalysis
Abstract

The aldol reaction of various arom. aldehydes with cyclohexanone catalyzed by the inclusion complex of a proline deriv. and beta-cyclodextrin in water is described.  A series of hydroxyketones was obtained using this method in good yields with anti/syn ratio of up to 99:1 and ee values well above 90%.

Publisher Georg Thieme
ISSN/ISBN 0936-5214
edoc-URL http://edoc.unibas.ch/dok/A5260125
Full Text on edoc No
Digital Object Identifier DOI 10.1055/s-2007-985569
ISI-Number WOS:000249394900033
Document type (ISI) Article
 
   

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