A short route to alpha -tocopherol
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID 163248
Author(s) Liu, Kegang; Chougnet, Antoinette; Woggon, Wolf-D
Author(s) at UniBasel Woggon, Wolf-Dietrich
Year 2008
Title A short route to alpha -tocopherol
Journal Angewandte Chemie. International edition in English
Volume 47
Number 31
Pages / Article-Number 5827-9
Keywords aldol reaction, decarboxylation, diastereoselectivity, Michael addition, vitamins

A simple and practical route to alpha-tocopherol (I) is described.  The key step is a remarkably diastereoselective domino aldol/oxa-Michael reaction, which is promoted by a proline deriv.

Publisher VCH
ISSN/ISBN 1521-3773
edoc-URL http://edoc.unibas.ch/dok/A5260122
Full Text on edoc No
Digital Object Identifier DOI 10.1002/anie.200801765
PubMed ID http://www.ncbi.nlm.nih.gov/pubmed/18576461
ISI-Number WOS:000257963900027
Document type (ISI) Journal Article

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