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Recombinant live Salmonella spp. for human vaccination against heterologous pathogens
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
 
ID 156882
Author(s) Bumann, D.; Hueck, C.; Aebischer, T.; Meyer, T. F.
Author(s) at UniBasel Bumann, Dirk
Year 2000
Title Recombinant live Salmonella spp. for human vaccination against heterologous pathogens
Journal FEMS Immunology and Medical Microbiology
Volume 27
Number 4
Pages / Article-Number 357-64
Keywords attenuated live carrier, clinical trial, Salmonella vaccine
Abstract Live attenuated Salmonella spp. are promising candidates as oral vaccine delivery systems for heterologous antigens. Clinical trials have demonstrated that this approach is feasible for human vaccinations but further optimisation is necessary to obtain a better efficacy. Here, we discuss how existing clinical and pre-clinical data can be used to guide such optimisation efforts.
Publisher Elsevier
ISSN/ISBN 0928-8244 ; 1574-695X
edoc-URL http://edoc.unibas.ch/dok/A5259831
Full Text on edoc Available
Digital Object Identifier DOI 10.1111/j.1574-695X.2000.tb01450.x
PubMed ID http://www.ncbi.nlm.nih.gov/pubmed/10727892
ISI-Number WOS:000086162700012
Document type (ISI) Journal Article, Review
 
   

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