Agrin, laminin beta 2 (s-laminin) and ARIA : their role in neuromuscular development
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID 155397
Author(s) Ruegg, M. A.
Author(s) at UniBasel Rüegg, Markus A.
Year 1996
Title Agrin, laminin beta 2 (s-laminin) and ARIA : their role in neuromuscular development
Journal Current Opinion in Neurobiology
Volume 6
Number 1
Pages / Article-Number 97-103
Keywords Agrin/*physiology; Animals; Gene Expression; Laminin/*physiology; Neuromuscular Junction/*physiology
Mesh terms Agrin, physiology; Animals; Gene Expression; Laminin, physiology; Neuromuscular Junction, physiology
Abstract Development of pre- and postsynaptic specializations at the vertebrate neuromuscular junction is affected by molecules concentrated in the extracellular matrix of the synaptic cleft. Agrin, laminin beta 2 and ARIA are the best characterized proteins known to be involved in particular aspects of synaptic differentiation. Recent advances in defining the domains of these molecules that are crucial for their synapse-organizing activity and their localization to synaptic basal lamina will help our understanding of the molecular mechanisms involved in synapse formation.
Publisher Elsevier
ISSN/ISBN 0959-4388
Full Text on edoc Restricted
Digital Object Identifier DOI 10.1016/S0959-4388(96)80014-6
PubMed ID
ISI-Number WOS:A1996UM23600014
Document type (ISI) Journal Article, Review

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