An amino acid shuffle activates mTORC1
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
 
ID 153740
Author(s) Cohen, A.; Hall, M. N.
Author(s) at UniBasel Hall, Michael N.
Year 2009
Title An amino acid shuffle activates mTORC1
Journal Cell
Volume 136
Number 3
Pages / Article-Number 399-401
Abstract

The mammalian target of rapamycin complex 1 (mTORC1), which promotes cell growth, is regulated by specific nutrients such as the amino acid leucine. In this issue, Nicklin et al. (2009) describe a mechanism by which glutamine facilitates the uptake of leucine, leading to mTORC1 activation.

Publisher Cell Press
ISSN/ISBN 0092-8674 ; 1097-4172
edoc-URL http://edoc.unibas.ch/dok/A5258122
Full Text on edoc No
Digital Object Identifier DOI 10.1016/j.cell.2009.01.021
PubMed ID http://www.ncbi.nlm.nih.gov/pubmed/19203575
ISI-Number WOS:000263120600010
Document type (ISI) Editorial Material
 
   

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