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Advanced parental age : a risk factor for Alzheimer's disease or depression in the elderly?
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
 
ID 149581
Author(s) Ptok, U; Papassotiropoulos, A; Maier, W; Heun, R
Author(s) at UniBasel Papassotiropoulos, Andreas
Year 2000
Title Advanced parental age : a risk factor for Alzheimer's disease or depression in the elderly?
Journal International psychogeriatrics
Volume 12
Number 4
Pages / Article-Number 445-51
Abstract

BACKGROUND: Advanced parental age has been suggested as a risk factor for Alzheimer's disease (AD) as well as for other psychiatric disorders. In the present investigation, a sample of gerontopsychiatric patients was examined for a possible parental age effect. STUDY POPULATION AND METHODS: Eighty-three patients with AD, 154 elderly patients with depressive episodes, and 48 comorbid patients (AD and depressive episode) as well as 107 age-matched healthy control subjects from the general population were included in the investigation. Information on the years of birth of the parents was derived from personal or family history information. RESULTS: The mean maternal and paternal ages at the time of birth of the index subject were not significantly different for the different diagnostic subgroups or for the control sample. CONCLUSION: There was no evidence in our sample that advanced parental age increases the risk of AD or depression in the elderly.

Publisher Cambridge University Press
ISSN/ISBN 1041-6102
edoc-URL http://edoc.unibas.ch/dok/A5257203
Full Text on edoc No
Digital Object Identifier DOI 10.1017/S1041610200006566
PubMed ID http://www.ncbi.nlm.nih.gov/pubmed/11263711
ISI-Number WOS:000167362300005
Document type (ISI) Journal Article
 
   

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