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SAPALDIA Off-spring study
Third-party funded project
Project title SAPALDIA Off-spring study
Principal Investigator(s) Dratva, Julia
Project Members Künzli, Nino
Zemp Stutz, Elisabeth
Probst Hensch, Nicole
Schindler, Christian
Felber Dietrich, Denise
Organisation / Research unit Swiss Tropical and Public Health Institute (Swiss TPH) / Gender and Health (Zemp Stutz)
Project start 01.06.2010
Probable end 30.11.2012
Status Completed

The SAPALDIA Youth Study aims at investigating the impact of early life and cumulative life-time ETS exposure on vascular health in the childhood, measured by intima media thickness. The study is based on the hypothesis that ETS exposure in pregnancy and childhood is associated with an increased intima media thickness, and further that the effect is amplified by recurrent childhood infectious diseases and chronic subclinical inflammation. These hypotheses are to be tested in a sample of 200 SAPALDIA off-spring, aged 10-20 years, to equal parts ETS exposed in pregnancy and childhood and non-exposed controls. The study is set withinthe third survey of the Swiss Air Pollution And Chronic Disease In Adults (SAPALDIA) cohort in 2010.

Keywords Early life factors, ETS exposure, Carotis Intima Media Thickness, Ateriosclerosis, Children
Financed by Swiss National Science Foundation (SNSF)
Foundations and Associations

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