Atomic force microscopy (AFM)-based tissue diagnostics is developing into a bio-medical mega-trend. We want to capitalize on the success of our current KTI project (“ARTIDIS”, Nr. 11977.2) by combining fast measurement speeds and increased accuracy with user-friendly operation. By developing ARTIDIS+, we are poised to occupy a leading position in the world market of nanomechanical diagnostics with strong societal impact.