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T Cell Biology in Health and Disease
| Third-party funded project |
| Project title |
T Cell Biology in Health and Disease |
| Principal Investigator(s) |
De Libero, Gennaro
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| Co-Investigator(s) |
De Libero, Gennaro
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| Organisation / Research unit |
Departement Biomedizin / Experimental Immunology (De Libero) |
| Project start |
01.07.2009 |
| Probable end |
30.06.2012 |
| Status |
Completed |
| Abstract |
Human health depends on a balanced functioning of immune defense mechanisms. This is especially true for T lymphocytes, one of the most important blood cells in the immune system. T lymphocytes play a critical role in protecting an individual from pathogenic bacteria, viruses and fungi in the environment. If someone has too few or poorly functioning T lymphocytes, they can develop serious infections. On the other hand, with overactive or poorly controlled T lymphocytes, one is at risk of developing an autoimmune disease, such as Diabetes, Multiple Sclerosis, Arthritis and Systemic Lupus. In this respect, good health requires the right balance T lymphocyte activity. The current project aims to understand the molecular and cellular basis of T lymphocytes in health and disease. The research consortium will be collaborating to understand how T lymphocytes cause autoimmunity and control infections. |
| Financed by |
Swiss National Science Foundation (SNSF)
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29/04/2024
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