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Epigenetics of ovarian cancer : from the lab to the clinic
Journal
Gynecologic oncology
Volume
118
Number
1
Pages
81-7
Keywords
Ovarian cancer, DNA methylation, Histone modification, MicroRNA, Prognosis, Treatment
Abstract
Ovarian cancer remains the most lethal gynaecological cancer. Various molecular changes have been identified and have shown promise for their diagnostic, prognostic and curative capacity but still need further validation. Among different mechanisms, the present article reviews the importance of epigenetic changes in ovarian cancer.
