Enhanced Th1 and Th17 responses and arthritis severity in mice with a deficiency of myeloid cell-specific interleukin-1 receptor antagonist

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Enhanced Th1 and Th17 responses and arthritis severity in mice with a deficiency of myeloid cell-specific interleukin-1 receptor antagonist

JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)

ID	1196628
Author(s)	Lamacchia, Céline; Palmer, Gaby; Seemayer, Christian A; Talabot-Ayer, Dominique; Gabay, Cem
Author(s) at UniBasel	Seemayer, Christian A.
Year	2010
Title	Enhanced Th1 and Th17 responses and arthritis severity in mice with a deficiency of myeloid cell-specific interleukin-1 receptor antagonist
Journal	Arthritis & rheumatism
Volume	62
Number	2
Pages / Article-Number	452-62
Abstract	The balance between interleukin-1 (IL-1) and its specific inhibitor, the IL-1 receptor antagonist (IL-1Ra), plays a major role in the development of arthritis. The purpose of this study was to investigate the role of IL-1Ra produced specifically by myeloid cells in the control of collagen-induced arthritis (CIA) by using myeloid cell-specific IL-1Ra-deficient mice (IL-1Ra(DeltaM)).
Publisher	Wiley-Liss
ISSN/ISBN	0004-3591
edoc-URL	http://edoc.unibas.ch/dok/A6006793
Full Text on edoc	No
Digital Object Identifier DOI	10.1002/art.27235
PubMed ID	http://www.ncbi.nlm.nih.gov/pubmed/20112392
ISI-Number	WOS:000279432100023
Document type (ISI)	Journal Article

14/05/2024

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