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Analgesic and antihyperalgesic properties of propofol in a human pain model
Journal
Anesthesiology
Volume
113
Number
2
Pages / Article-Number
421-8
Abstract
Propofol (Disoprivan, AstraZeneca AG, Zug, Switzerland) has long been considered to be nonanalgesic. However, accumulating evidence shows that propofol possesses modulatory action on pain processing and perception. In this study, the authors investigated the modulatory effects of propofol and a formulation similar to the solvent of propofol (10% Intralipid; Fresenius Kabi, Stans, Switzerland) on pain perception and central sensitization in healthy volunteers.
