A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
 
ID 1196498
Author(s) Kappos, Ludwig; Radue, Ernst-Wilhelm; O'Connor, Paul; Polman, Chris; Hohlfeld, Reinhard; Calabresi, Peter; Selmaj, Krzysztof; Agoropoulou, Catherine; Leyk, Malgorzata; Zhang-Auberson, Lixin; Burtin, Pascale; FREEDOMS Study Group
Author(s) at UniBasel Kappos, Ludwig
Year 2010
Title A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis
Journal The New England journal of medicine
Volume 362
Number 5
Pages / Article-Number 387-401
Abstract Oral fingolimod, a sphingosine-1-phosphate-receptor modulator that prevents the egress of lymphocytes from lymph nodes, significantly improved relapse rates and end points measured on magnetic resonance imaging (MRI), as compared with either placebo or intramuscular interferon beta-1a, in phase 2 and 3 studies of multiple sclerosis.
Publisher Massachusetts Medical Society
ISSN/ISBN 1533-4406
edoc-URL http://edoc.unibas.ch/dok/A6006665
Full Text on edoc No
Digital Object Identifier DOI 10.1056/NEJMoa0909494
PubMed ID http://www.ncbi.nlm.nih.gov/pubmed/20089952
ISI-Number WOS:000274193300005
Document type (ISI) Journal Article, Multicenter Study, Randomized Controlled Trial
 
   

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