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A comprehensive analysis of p16 expression, gene status, and promoter hypermethylation in surgically resected non-small cell lung carcinomas
Journal
Journal of thoracic oncology
Volume
6
Number
10
Pages / Article-Number
1649-57
Keywords
p16, Expression, Deletion, Hypermethylation, Non-small cell lung cancer
Abstract
The role of p16 is gaining importance in non-small cell lung cancer (NSCLC) because of epigenetic therapy options. Further insight into the significance of protein expression, gene status and promoter methylation is needed and has the potential to optimize existing treatment strategies.
