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Prevalence of airflow obstruction in smokers and never smokers in Switzerland
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID 1195966
Author(s) Bridevaux, P.-O.; Probst-Hensch, N. M.; Schindler, C.; Curjuric, I.; Felber Dietrich, D.; Braendli, O.; Brutsche, M.; Burdet, L.; Frey, M.; Gerbase, M. W.; Ackermann-Liebrich, U.; Pons, M.; Tschopp, J.-M.; Rochat, T.; Russi, E. W.
Author(s) at UniBasel Brutsche, Martin
Felber Dietrich, Denise
Curjuric, Ivan
Ackermann-Liebrich, Ursula A.
Probst Hensch, Nicole
Schindler, Christian
Year 2010
Title Prevalence of airflow obstruction in smokers and never smokers in Switzerland
Journal The European respiratory journal
Volume 36
Number 6
Pages / Article-Number 1259-69
Keywords Asthma, bronchial hyperreactivity, chronic obstructive pulmonary disease, population study, sex differences, smoking
Abstract We aimed to measure age-specific prevalence of airflow obstruction (AO) in Switzerland in smokers and never smokers using pulmonary function tests and respiratory symptoms from 6126 subjects participating in the Swiss Cohort Study on Air Pollution and Lung Diseases in Adults.The lower limit of normal of FEV1/FVC ratio was used to define AO. Severity of AO was graded according to the recommendations of the Global Initiative for Chronic Obstructive Lung Disease.Prevalence of AO ranged from 2.5% in subjects aged 30-39 to 8.0% in those aged 70 or more. In multivariate analysis, age (ORaged70+ vs aged 30-39 2.8), smoking (OR 1.8) and asthma, (OR 6.7) were associated with AO. Never smokers constituted 29.3 % of subjects with AO. Never smokers with AO were younger, male and reported more frequently asthma than obstructive smokers. Obstructive smokers and never smokers had similar level of symptoms and quality of life impairment.Prevalence of AO in Switzerland is similar in magnitude compared to other developed countries. Never smokers account for a third of the prevalence which is higher than elsewhere. AO in never smokers deserve attention because of its frequency and its similar health impact than in smokers
Publisher Munksgaard
ISSN/ISBN 0903-1936
Full Text on edoc No
Digital Object Identifier DOI 10.1183/09031936.00004110
PubMed ID
ISI-Number WOS:000284765600008
Document type (ISI) Journal Article

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