Spinal epidural abscess : aetiology, predisponent factors and clinical outcomes in a 4-year prospective study
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID 1195824
Author(s) Zimmerer, Stephan M E; Conen, Anna; Müller, Andreas A; Sailer, Martin; Taub, Ethan; Flückiger, Ursula; Schwenzer-Zimmerer, Katja C
Author(s) at UniBasel Flückiger, Ursula M.
Conen, Anna
Year 2011
Title Spinal epidural abscess : aetiology, predisponent factors and clinical outcomes in a 4-year prospective study
Journal European spine journal
Volume 20
Number 12
Pages / Article-Number 2228-34
Keywords Spinal epidural abscess (SEA), Surgical site infection (SSI), Focal infection, Staphylococcus aureus, Instrumented surgery

Spinal epidural abscess (SEA) is a rare, but serious, condition with multiple causes. We prospectively studied the aetiology, predisposing factors, and clinical outcomes of SEA in all patients with SEA treated in our hospital's neurosurgical service from 2004 to 2008. For each patient, we recorded the medical history, comorbidities, focus of infection, pathogen(s), and outcome. The 36 patients (19 women and 17 men) ranged in age from 34 to 80 years old (mean 57; median 56). The SEA was primary (i.e., due to haematogenous spread) in 16 patients (44%); it was secondary to elective spinal procedures, either injections or surgery, in 20 patients (56%). The duration of follow-up was 12-60 months (mean 36; median 37.5). The most common pathogen, Staphylococcus aureus, was found in 18 patients (50%). Patients with primary SEA had different underlying diseases and a wider range of pathogens than those with secondary SEA. Only five patients (14%) had no major comorbidity; 16 of the 20 patients with secondary SEA (44% of the overall group) had undergone spinal surgery before developing the SEA; the treatment of the SEA involved multiple surgical operations in all 16 of these patients, and spinal instrumentation in 5 (14%); 22 patients (61% of the overall group) recovered fully.

Publisher Springer
ISSN/ISBN 0940-6719
edoc-URL http://edoc.unibas.ch/dok/A6006005
Full Text on edoc No
Digital Object Identifier DOI 10.1007/s00586-011-1838-y
PubMed ID http://www.ncbi.nlm.nih.gov/pubmed/21590496
ISI-Number WOS:000297749400021
Document type (ISI) Article

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