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Interruptions of cART limits CD4 T-cell recovery and increases the risk for opportunistic complications and death
Journal
AIDS
Volume
25
Number
4
Pages / Article-Number
441-51
Keywords
CD4 T cells, combination antiretroviral therapy, HIV infection, immunological recovery, interruptions
Abstract
A major goal of antiretroviral therapy (ART) for HIV-1-infected persons is the recovery of CD4 T lymphocytes, resulting in thorough protection against opportunistic complications. Interruptions of ART are still frequent. The long-term effect on CD4 T-cell recovery and clinical events remains unknown.
