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Analyses adjusting for selective crossover show improved overall survival with adjuvant letrozole compared with tamoxifen in the BIG 1-98 study
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
 
ID 1195706
Author(s) Colleoni, Marco; Giobbie-Hurder, Anita; Regan, Meredith M; Thürlimann, Beat; Mouridsen, Henning; Mauriac, Louis; Forbes, John F; Paridaens, Robert; Láng, István; Smith, Ian; Chirgwin, Jacquie; Pienkowski, Tadeusz; Wardley, Andrew; Price, Karen N; Gelber, Richard D; Coates, Alan S; Goldhirsch, Aron
Author(s) at UniBasel Thürlimann, Beat
Year 2011
Title Analyses adjusting for selective crossover show improved overall survival with adjuvant letrozole compared with tamoxifen in the BIG 1-98 study
Journal Journal of clinical oncology
Volume 29
Number 9
Pages / Article-Number 1117-24
Abstract Among postmenopausal women with endocrine-responsive breast cancer, the aromatase inhibitor letrozole, when compared with tamoxifen, has been shown to significantly improve disease-free survival (DFS) and time to distant recurrence (TDR). We investigated whether letrozole monotherapy prolonged overall survival (OS) compared with tamoxifen monotherapy.
Publisher American Society of Clinical Oncology
ISSN/ISBN 0732-183X
edoc-URL http://edoc.unibas.ch/dok/A6005887
Full Text on edoc No
Digital Object Identifier DOI 10.1200/JCO.2010.31.6455
PubMed ID http://www.ncbi.nlm.nih.gov/pubmed/21321298
ISI-Number WOS:000288532500023
Document type (ISI) Journal Article, Randomized Controlled Trial
 
   

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