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Esophageal strictures in adult eosinophilic esophagitis: dilation is an effective and safe alternative after failure of topical corticosteroids
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
 
ID 1195637
Author(s) Schoepfer, A. M.; Gschossmann, J.; Scheurer, U.; Seibold, F.; Straumann, A.
Author(s) at UniBasel Straumann, Alex
Year 2008
Title Esophageal strictures in adult eosinophilic esophagitis: dilation is an effective and safe alternative after failure of topical corticosteroids
Journal Endoscopy
Volume 40
Number 2
Pages / Article-Number 161-4
Mesh terms Administration, Topical; Adolescent; Adrenal Cortex Hormones, therapeutic use; Adult; Catheterization, methods; Child; Child, Preschool; Cohort Studies; Eosinophilia, complications; Esophageal Stenosis, therapy; Esophagitis, complications; Esophagoscopy, methods; Female; Follow-Up Studies; Humans; Male; Retrospective Studies; Risk Assessment; Severity of Illness Index; Treatment Failure
Abstract Strictures are a frequent complication of eosinophilic esophagitis. The efficacy and safety of topical corticosteroids and of dilation of eosinophilic esophagitis-associated strictures have not yet been thoroughly clarified. We present a retrospective analysis of 10 adult patients with eosinophilic esophagitis who had symptomatic esophageal stenosis that was unresponsive to topical corticosteroids, and who were treated using bougienage. Eight patients had one single stricture, one patient had two, and another had three strictures; mean stricture length was 2.1 cm (range 1 - 6 cm). Bougienage led to prompt symptom relief. Apart from transient postprocedural odynophagia, no severe complications occurred. During the follow-up (mean 6 months; range 2 - 11 months), all patients enjoyed sustained treatment response.
Publisher Georg Thieme
ISSN/ISBN 0013-726X ; 1438-8812
edoc-URL https://edoc.unibas.ch/62940/
Full Text on edoc No
Digital Object Identifier DOI 10.1055/s-2007-995345
PubMed ID http://www.ncbi.nlm.nih.gov/pubmed/18253909
ISI-Number WOS:000253676800014
Document type (ISI) Journal Article, Multicenter Study
 
   

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