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Risk factors for chemotherapy-induced neutropenia occurrence in breast cancer patients : data from the INC-EU Prospective Observational European Neutropenia Study
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID
1195225
Author(s)
Schwenkglenks, Matthias; Pettengell, Ruth; Jackisch, Christian; Paridaens, Robert; Constenla, Manuel; Bosly, André; Szucs, Thomas D; Leonard, Robert
Risk factors for chemotherapy-induced neutropenia occurrence in breast cancer patients : data from the INC-EU Prospective Observational European Neutropenia Study
Journal
Supportive care in cancer
Volume
19
Number
4
Pages / Article-Number
483-90
Keywords
Neutropenia, Chemotherapy, Breast cancer, Risk factors
Abstract
Chemotherapy-induced neutropenia (CIN) places patients at risk of life-threatening infections. While reduction of chemotherapy dose or delay of the subsequent treatment cycle and, consequently, reduction of relative dose intensity (RDI) may limit myelotoxicity, these actions can also impact adversely on treatment outcome and should be avoided in adjuvant settings.
