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Efficacy, tolerability and risk factors for virological failure of darunavir-based therapy for treatment-experienced HIV-infected patients : the Swiss HIV Cohort Study
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID
1194522
Author(s)
Young, J; Scherrer, A U; Günthard, H F; Opravil, M; Yerly, S; Böni, J; Rickenbach, M; Fux, C A; Cavassini, M; Bernasconi, E; Vernazza, P; Hirschel, B; Battegay, M; Bucher, H C; Swiss HIV Cohort Study
Efficacy, tolerability and risk factors for virological failure of darunavir-based therapy for treatment-experienced HIV-infected patients : the Swiss HIV Cohort Study
Journal
HIV medicine
Volume
12
Number
5
Pages / Article-Number
299-307
Keywords
Bayes theorem, HIV drug resistance, protease inhibitors, risk factors, salvage therapy, viral load
Abstract
Darunavir was designed for activity against HIV resistant to other protease inhibitors (PIs). We assessed the efficacy, tolerability and risk factors for virological failure of darunavir for treatment-experienced patients seen in clinical practice.