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ADME pharmacogenetics : investigation of the pharmacokinetics of the antiretroviral agent lopinavir coformulated with ritonavir
Journal
Pharmacogenetics and genomics
Volume
20
Number
4
Pages / Article-Number
217-30
Keywords
absorption, distribution, metabolism and excretion, lopinavir, pharmacogenetics, population pharmacokinetics
Abstract
An ADME (absorption, distribution, metabolism and excretion)-pharmacogenetics association study may identify functional variants relevant to the pharmacokinetics of lopinavir co-formulated with ritonavir (LPV/r), a first-line anti-HIV agent.