Antihistamines are superior to topical steroids in managing human immunodeficiency virus (HIV)-associated papular pruritic eruption
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
 
ID 1194059
Author(s) Navarini, Alexander A.; Stoeckle, Marcel; Navarini, Susanne; Mossdorf, Erik; Jullu, Boniphace S.; Mchomvu, Rehema; Mbata, Marco; Kibatala, Patience; Tanner, Marcel; Hatz, Christoph; Schmid-Grendelmeier, Peter
Author(s) at UniBasel Tanner, Marcel
Year 2010
Title Antihistamines are superior to topical steroids in managing human immunodeficiency virus (HIV)-associated papular pruritic eruption
Journal International journal of dermatology
Volume 49
Number 1
Pages / Article-Number 83-6
Abstract Papular pruritic eruption (PPE) is a frequent HIV-comorbidity in tropical countries. Because of constant itching and social stigma, effective treatment is highly valued. In our HIV cohort in rural Tanzania with 12% prevalence of PPE, we have retrospectively analyzed responses to available treatments. Oral promethazine improved itching (P > 0.0058) and clinical scores (P > 0.032) significantly more than topical steroids. Disease activity did not correlate with CD4+ and CD8+ T cell counts and was independent of anti-retroviral medication. Therefore, oral antihistamines are an effective first-line treatment for PPE
Publisher WILEY-BLACKWELL PUBLISHING, INC
ISSN/ISBN 0011-9059
edoc-URL http://edoc.unibas.ch/dok/A5842814
Full Text on edoc No
Digital Object Identifier DOI 10.1111/j.1365-4632.2009.04279.x
PubMed ID http://www.ncbi.nlm.nih.gov/pubmed/20465620
ISI-Number WOS:000272865700019
Document type (ISI) Journal Article
 
   

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