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Beyond hematoxylin and eosin : the importance of immunohistochemical techniques for evaluating surgically resected constipated patients
Journal
Techniques in coloproctology
Volume
15
Number
4
Pages / Article-Number
371-5
Keywords
Constipation, Histology, Immunohistochemistry, Surgery
Abstract
Chronic constipation requiring surgical ablation for intractability is often a frustrating condition from the pathologist's point of view. In fact, limiting the histological examination to only hematoxylin-eosin staining usually yields only the information that there are no abnormalities. By employing some simple and widely available immunohistochemical methods, discussed in this review, it is possible to gather data that may help in explaining the pathophysiological basis of constipation in these patients.