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Age modifies the relative risk of stenting versus endarterectomy for symptomatic carotid stenosis : a pooled analysis of EVA-3S, SPACE and ICSS
Journal
European journal of vascular and endovascular surgery
Volume
41
Number
2
Pages / Article-Number
153-8
Keywords
Symptomatic carotid stenosis, Stenting, Endarterectomy, Individual patient data meta-analysis, Age
Abstract
Recent randomised controlled trials comparing carotid artery stenting (CAS) with endarterectomy (CEA) for the treatment of symptomatic carotid stenosis were not powered to investigate differences in risks in specific patient subgroups. We therefore performed a pooled analysis of individual patient data from the Symptomatic Severe Carotid Stenosis trial (EVA-3S), the Stent-Protected Angioplasty versus Carotid Endarterectomy trial (SPACE), and the International Carotid Stenting Study (ICSS).