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Anti-interleukin-5 antibody treatment (mepolizumab) in active eosinophilic oesophagitis : a randomised, placebo-controlled, double-blind trial
Journal
Gut
Volume
59
Number
1
Pages / Article-Number
21-30
Abstract
Eosinophilic oesophagitis (EoO) is a clinicopathological condition defined by proton pump inhibitor-refractory oesophageal symptoms combined with oesophageal eosinophilia. The pharmacodynamic effect of mepolizumab (a humanised anti-interleukin-5 monoclonal antibody) in EoO was evaluated.