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Meta-analysis of combined therapy with angiotensin receptor antagonists versus ACE inhibitors alone in patients with heart failure
Journal
PLoS ONE
Volume
5
Number
4
Pages / Article-Number
e9946
Mesh terms
Angiotensin II Type 1 Receptor Blockers, therapeutic use; Angiotensin-Converting Enzyme Inhibitors, therapeutic use; Drug Therapy, Combination; Heart Failure, mortality; Hospitalization; Humans; Hypotension, chemically induced; Randomized Controlled Trials as Topic; Renal Insufficiency, chemically induced; Risk Assessment; Survival Rate
Abstract
There is insufficient evidence whether the benefit of adding angiotensin II receptor blockers (ARBs) to angiotensin-converting enzyme (ACE) inhibitors outweighs the increased risk of adverse effects in patients with heart failure.
