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The influence of tumor- and treatment-related factors on the development of local recurrence in osteosarcoma after adequate surgery : an analysis of 1355 patients treated on neoadjuvant Cooperative Osteosarcoma Study Group protocols
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID
1193173
Author(s)
Andreou, D; Bielack, S S; Carrle, D; Kevric, M; Kotz, R; Winkelmann, W; Jundt, G; Werner, M; Fehlberg, S; Kager, L; Kühne, T; Lang, S; Dominkus, M; Exner, G U; Hardes, J; Hillmann, A; Ewerbeck, V; Heise, U; Reichardt, P; Tunn, P-U
The influence of tumor- and treatment-related factors on the development of local recurrence in osteosarcoma after adequate surgery : an analysis of 1355 patients treated on neoadjuvant Cooperative Osteosarcoma Study Group protocols
Journal
Annals of oncology
Volume
22
Number
5
Pages / Article-Number
1228-35
Keywords
biopsy, limb-sparing surgery, local recurrence, osteosarcoma, surgical margin width
Abstract
Local recurrence (LR) in osteosarcoma is associated with very poor prognosis. We sought to evaluate which factors correlate with LR in patients who achieved complete surgical remission with adequate margins.
