An Iron-Based Molecular Redox Switch as a Model for Iron Release from Enterobactin via the Salicylate Binding Mode
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
 
ID 116792
Author(s) Ward, Thomas R.; Lutz, Andreas; Parel, Serge P.; Ensling, Juergen; Guetlich, Philipp; Buglyo, Peter; Orvig, Chris
Author(s) at UniBasel Ward, Thomas R.
Year 1999
Title An Iron-Based Molecular Redox Switch as a Model for Iron Release from Enterobactin via the Salicylate Binding Mode
Journal Inorganic Chemistry
Volume 38
Number 22
Pages / Article-Number 5007-5017
Keywords Isomers (linkage; of iron(II) vs. iron(III) to salicylamide bipyridine tripodal ligands); Formation constant; Reduction potential (of iron salicylamide bipyridine tripodal complexes); Coordination (of iron(II) vs. iron(III) to salicylamide bipyridine tripodal ligands); Protonation (of salicylamide bipyridine tripodal ligands); Molecular structure (optimized; of iron salicylamide bipyridine tripodal ligand complexes); enterobactin iron release model mol redox switch; iron salicylamide bipyridine
Abstract The iron release mechanism from protonated ferric enterobactin [FeIII(enterobactinH3)] via the salicylate binding mode was probed. For this purpose, a tripodal dodecadentate ligand incorporating three salicylamide (OO) and three bipyridine (NN) binding sites was synthesized as well as iron complexes thereof. It was shown that a ferric ion coordinates selectively to the hard salicylamides and a ferrous ion binds to the softer bipyridines. Upon reduction or oxidation, the iron translocates reversibly and intramolecularly from one site to the other, thus displaying switchlike properties. Both states were characterized by cyclic voltammetry and visible and Mössbauer spectroscopy. The Mössbauer spectrum for the ferric complex is fully consistent with that obtained by Pecoraro et al. upon lowering the pH of [FeIII(enterobactin)]3- solutions (Pecoraro, V. L., et al. J. Am. Chem. Soc. 1983, 105, 4617), thus supporting the alternative iron release mechanism from enterobactin via the salicylate binding mode.
Publisher American Chemical Society
ISSN/ISBN 0020-1669 ; 1520-510X
edoc-URL http://edoc.unibas.ch/dok/A5254506
Full Text on edoc No
Digital Object Identifier DOI 10.1021/ic990225e
ISI-Number WOS:000083670200015
Document type (ISI) Article
 
   

MCSS v5.8 PRO. 0.437 sec, queries - 0.000 sec ©Universität Basel  |  Impressum   |    
07/08/2020