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Prescribed medications and pharmacy interventions for acute respiratory tract infections in Swiss primary care
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
 
ID 107285
Author(s) Hersberger, K E; Botomino, A; Sarkar, R; Tschudi, P; Bucher, H C; Briel, M
Author(s) at UniBasel Hersberger, Kurt
Bucher, Heiner
Briel, Matthias
Year 2009
Title Prescribed medications and pharmacy interventions for acute respiratory tract infections in Swiss primary care
Journal Journal of clinical pharmacy and therapeutics
Volume 34
Number 4
Pages / Article-Number 387-95
Keywords antibiotic therapy, community pharmacy services, prescription quality, primary care, respiratory tract infections, symptomatic treatment
Abstract

BACKGROUND AND OBJECTIVES: Symptomatic medications are often not considered in clinical studies assessing interventions to reduce prescribing of antibiotics for acute respiratory tract infections (ARTI). Our study objectives were to examine prescribing patterns of antibiotics and symptomatic medications for ARTI in Swiss primary care and to monitor pharmacists' interventions during the prescription-dispensing process. METHODS: Medical records of 695 patients participating in a clinical trial which was designed to reduce use of antibiotics for ARTI in primary care, were linked to their prescriptions. Matching of prescribed and dispensed medications enabled the assessment of interventions by community pharmacists. RESULTS: On average, 2.4 different drugs were prescribed per patient (in total 142 antibiotics, 1599 symptomatic medications, and 56 non-ARTI-medication). Most patients (80%) were treated only with symptomatic medications. Most frequently prescribed symptomatic ARTI-medications were nasal decongestants (39%), cough suppressants (36%), and mucolytics (31%). Patients with prescribed antibiotics received significantly fewer symptomatic medications (odds ratio, 0.24; 95% confidence interval 0.16-0.37). Over 20% of prescriptions prompted at least one intervention by a pharmacist in the dispensing process. A discrepancy between prescribed and dispensed medications was seen in 19% of patients. CONCLUSIONS: Prescription rates of antibiotics for ARTI in this trial were low and patients were treated mainly with non-antibiotic symptomatic medications. Efforts to reduce antibiotic prescribing may induce higher rates of use of medications for intensive symptomatic treatment. Considerable differences between prescribed and dispensed medications were noted.

Publisher Blackwell
ISSN/ISBN 0269-4727
edoc-URL http://edoc.unibas.ch/dok/A5253534
Full Text on edoc No
Digital Object Identifier DOI 10.1111/j.1365-2710.2009.01049.x
PubMed ID http://www.ncbi.nlm.nih.gov/pubmed/19583671
ISI-Number WOS:000267753700003
Document type (ISI) Journal Article
 
   

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