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Fundamental progress in investigating drug resistance with electronic multidrug compliance monitoring (e-MCM)
Journal
Journal of Patient Compliance
Volume
1
Number
2
Pages / Article-Number
42-47
Keywords
Compliance, Drug resistance, Electronic Multidrug Compliance Monitoring, Pharmacological Biomarker
Abstract
Current definitions of drug resistance are shaped by the pharmacotherapeutic fields they occurred in. They usually mention various contributing factors and refer either to the clinical or the biomarker level. Particular attention has been attracted by antiplatelet resistance, a phenomenon with clinical, cellular and pharmacogenetical contributors. However, the impact of every single factor to antiplatelet resistance in outpatients under prescribed antiplatelet therapy has not been comprehensively evaluated so far, neither has the temporal pattern of drug intake been studied as a possible contributor.
