Antiprotozoal alkaloids from Galanthus trojanus
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID 1022829
Author(s) Kaya, Gulen Irem; Sarikaya, Buket; Onur, Mustafa Ali; Somer, Nehir Unver; Viladomat, Francesc; Codina, Carles; Bastida, Jaume; Lauinger, Ina L.; Kaiser, Marcel; Tasdemir, Deniz
Author(s) at UniBasel Kaiser, Marcel
Year 2011
Title Antiprotozoal alkaloids from Galanthus trojanus
Journal Phytochemistry letters
Volume 4
Number 3
Pages / Article-Number 301-305
Keywords Galanthus trojanus, Amaryllidaceae, Antimalarial activity, Alkaloid N-oxides
Abstract Two new alkaloid N-oxides, 1-O-acetyldihydromethylpseudolycorine N-oxide, and 11-hydroxyvittatine N-oxide, ten known alkaloids; arolycoricidine, haemanthamine, O-methylnorbelladine, narcidine, dihydrolycorine, 8-O-demethylmaritidine, stylopine and protopine, nicotinic acid and tyramine were isolated from Galanthus trojanus A. P. Davis & N. Ozhatay (Amaryllidaceae). The chemical structures of the isolates were elucidated by UV, IR, MS, CD, 1D and 2D NMR experiments. The in vitro antiprotozoal and cytotoxic potentials of the compounds were also evaluated. (C) 2011 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
Publisher Elsevier
ISSN/ISBN 1874-3900
Full Text on edoc No
Digital Object Identifier DOI 10.1016/j.phytol.2011.05.008
ISI-Number WOS:000296534500021
Document type (ISI) Article

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