Centrosome regulation during the cell cycle
Project funded by own resources
Project title Centrosome regulation during the cell cycle
Principal Investigator(s) Nigg, Erich
Organisation / Research unit Departement Biozentrum,
Departement Biozentrum / Cell Biology (Nigg)
Project Website www.biozentrum.unibas.ch/nigg/personal/research.html
Project start 01.01.2005
Probable end 01.11.2017
Status Completed
Abstract

We are studying the structure, duplication and function of the centrosome, the major microtubule organizing center of animal cells. In particular, we are interested in the regulation of PLK4 and its role in centrosome/centriole duplication as well as the function of other centrosomal proteins. We are also exploring mechanisms underlying centriole biogenesis and the formation of cilia.

Lab members involved: G. Guderian, K. Mayer, J. Westendorf (former member), T. Schmidt (MPIB), E. Nigg, EA. Nigg

Financed by University funds
   

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