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Centrosome regulation during the cell cycle
| Project funded by own resources |
| Project title |
Centrosome regulation during the cell cycle |
| Principal Investigator(s) |
Nigg, Erich
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| Organisation / Research unit |
Departement Biozentrum,
Departement Biozentrum / Cell Biology (Nigg) |
| Project Website |
www.biozentrum.unibas.ch/nigg/personal/research.html |
| Project start |
01.01.2005 |
| Probable end |
01.11.2017 |
| Status |
Completed |
| Abstract |
We are studying the structure, duplication and function of the centrosome, the major microtubule organizing center of animal cells. In particular, we are interested in the regulation of PLK4 and its role in centrosome/centriole duplication as well as the function of other centrosomal proteins. We are also exploring mechanisms underlying centriole biogenesis and the formation of cilia.
Lab members involved: G. Guderian, K. Mayer, J. Westendorf (former member), T. Schmidt (MPIB), E. Nigg, EA. Nigg |
| Financed by |
University funds
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19/04/2024
Research Database / FORSCHUNGSDATENBANK
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