Publications
Showing records 1 - 20 (of 24)
Publication: JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID
Author
Year
Title
Publisher
4696037 Lamers, Christina; Ricklin, Daniel; Lambris, John D
2023
Complement-targeted therapeutics: An emerging field enabled by academic drug discovery.
American journal of hematology
4645235 Lamers, Christina; Mastellos, Dimitrios C; Ricklin, Daniel; Lambris, John D
2022
Compstatins: the dawn of clinical C3-targeted complement inhibition.
Trends in pharmacological sciences
4650955 Bechtler, Clément; Koutsogiannaki, Sophia; Umnyakova, Ekaterina; Hamid, Amal; Gautam, Avneesh; Sarigiannis, Yiannis; Pouw, Richard B; Lamers, Christina; Rabbani, Said; Schmidt, Christoph Q; Lambris, John D; Ricklin, Daniel
2022
Complement-regulatory biomaterial coatings: activity and selectivity profile of the factor H-binding peptide 5C6.
Acta biomaterialia
4649705 Lamers, Christina; Xue, Xiaoguang; Smiesko, Martin; van Son, Henri; Wagner, Bea; Berger, Nadja; Sfyroera, Georgia; Gros, Piet; Lambris, John D; Ricklin, Daniel
2022
Insight into mode-of-action and structural determinants of the compstatin family of clinical complement inhibitors.
Nature communications
4625491 Schwardt, Oliver; Lamers, Christina; Bechtler, Clément; Ricklin, Daniel
2021
Therapeutic Peptides as Emerging Options to Restore Misguided Host Defence and Homeostasis: From Teaching to Concept to Clinic.
Chimia
4625488 Lamers, Christina; Plüss, Carla Johanna; Ricklin, Daniel
2021
The Promiscuous Profile of Complement Receptor 3 in Ligand Binding, Immune Modulation, and Pathophysiology.
Frontiers in immunology
4614033 Wilbs, Jonas; Kong, Xu-Dong; Middendorp, Simon J; Prince, Raja; Cooke, Alida; Demarest, Caitlin T; Abdelhafez, Mai M; Roberts, Kalliope; Umei, Nao; Gonschorek, Patrick; Lamers, Christina; Deyle, Kaycie; Rieben, Robert; Cook, Keith E; Angelillo-Scherrer, Anne; Heinis, Christian
2020
Cyclic peptide FXII inhibitor provides safe anticoagulation in a thrombosis model and in artificial lungs.
Nature communications
4500837 Flesch, Daniel; Cheung, Sun-Yee; Schmidt, Jurema; Gabler, Matthias; Heitel, Pascal; Kramer, Jan; Kaiser, Astrid; Hartmann, Markus; Lindner, Mara; Lüddens-Dämgen, Kerstin; Heering, Jan; Lamers, Christina; Lüddens, Hartmut; Wurglics, Mario; Proschak, Ewgenij; Schubert-Zsilavecz, Manfred; Merk, Daniel
2017
Nonacidic Farnesoid X Receptor Modulators
Journal of Medicinal Chemistry
4501194 Lamers, Christina; Merk, Daniel; Gabler, Matthias; Flesch, Daniel; Kaiser, Astrid; Schubert-Zsilavecz, Manfred
2016
SAR studies on FXR modulators led to the discovery of the first combined FXR antagonistic/TGR5 agonistic compound
Future medicinal chemistry
4501195 Blöcher, René; Lamers, Christina; Wittmann, Sandra K.; Merk, Daniel; Hartmann, Markus; Weizel, Lilia; Diehl, Olaf; Brüggerhoff, Astrid; Boß, Marcel; Kaiser, Astrid; Schader, Tim; Göbel, Tamara; Grundmann, Manuel; Angioni, Carlo; Heering, Jan; Geisslinger, Gerd; Wurglics, Mario; Kostenis, Evi; Brüne, Bernhard; Steinhilber, Dieter; Schubert-Zsilavecz, Manfred; Kahnt, Astrid S.; Proschak, Ewgenij
2016
N-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase/Peroxisome Proliferator-Activated Receptor γ Modulators
Journal of medicinal chemistry
4501196 Merk, Daniel; Lamers, Christina; Weber, Julia; Flesch, Daniel; Gabler, Matthias; Proschak, Ewgenij; Schubert-Zsilavecz, Manfred
2015
Anthranilic acid derivatives as nuclear receptor modulators--development of novel PPAR selective and dual PPAR/FXR ligands
Bioorganic & medicinal chemistry
4501197 Flesch, Daniel; Ness, Julia; Lamers, Christina; Dehm, Friederike; Popella, Sven; Steri, Ramona; Ogorek, Isabella; Hieke, Martina; Dannhardt, Gerd; Werz, Oliver; Weggen, Sascha; Schubert-Zsilavecz, Manfred
2015
SAR-studies of γ-secretase modulators with PPARγ-agonistic and 5-lipoxygenase-inhibitory activity for Alzheimer's disease
Bioorganic and Medicinal Chemistry Letters
4501198 Reker, Daniel; Perna, Anna M.; Rodrigues, Tiago; Schneider, Petra; Reutlinger, Michael; Mönch, Bettina; Koeberle, Andreas; Lamers, Christina; Gabler, Matthias; Steinmetz, Heinrich; Müller, Rolf; Schubert-Zsilavecz, Manfred; Werz, Oliver; Schneider, Gisbert
2014
Revealing the macromolecular targets of complex natural products
Nature Chemistry
4501203 Merk, Daniel; Gabler, Matthias; Gomez, Roberto Carrasco; Flesch, Daniel; Hanke, Thomas; Kaiser, Astrid; Lamers, Christina; Werz, Oliver; Schneider, Gisbert; Schubert-Zsilavecz, Manfred
2014
Anthranilic acid derivatives as novel ligands for farnesoid X receptor (FXR)
Bioorganic & medicinal chemistry
4501202 Lamers, Christina; Dittrich, Michaela; Steri, Ramona; Proschak, Ewgenij; Schubert-Zsilavecz, Manfred
2014
Molecular determinants for improved activity at PPARα: structure-activity relationship of pirinixic acid derivatives, docking study and site-directed mutagenesis of PPARα
Bioorganic and Medicinal Chemistry Letters
4501201 Hanke, Thomas; Lamers, Christina; Gomez, Roberto Carrasco; Schneider, Gisbert; Werz, Oliver; Schubert-Zsilavecz, Manfred
2014
Identification of pirinixic acid derivatives bearing a 2-aminothiazole moiety combines dual PPARα/γ activation and dual 5-LO/mPGES-1 inhibition
Bioorganic and Medicinal Chemistry Letters
4501200 Merk, Daniel; Lamers, Christina; Ahmad, Khalil; Carrasco Gomez, Roberto; Schneider, Gisbert; Steinhilber, Dieter; Schubert-Zsilavecz, Manfred
2014
Extending the structure-activity relationship of anthranilic acid derivatives as farnesoid X receptor modulators: development of a highly potent partial farnesoid X receptor agonist
Journal of Medicinal Chemistry
4501199 Lamers, Christina; Schubert-Zsilavecz, Manfred; Merk, Daniel
2014
Medicinal chemistry and pharmacological effects of Farnesoid X Receptor (FXR) antagonists
Current Topics in Medicinal Chemistry
4501205 Lamers, Christina; Flesch, Daniel; Schubert-Zsilavecz, Manfred; Merk, Daniel
2013
Novel prostaglandin receptor modulators: a patent review (2002 - 2012) - part I: non-EP receptor modulators
Expert opinion on therapeutic patents
4501204 Flesch, Daniel; Merk, Daniel; Lamers, Christina; Schubert-Zsilavecz, Manfred
2013
Novel prostaglandin receptor modulators - part II: EP receptor modulators; a patent review (2002 - 2012)
Expert opinion on therapeutic patents
Showing records 1 - 20 (of 24)
