Publications
Showing records 1 - 20 (of 50)
Publication: JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID
Author
Year
Title
Publisher
4621125 Borsari, Chiara; Keles, Erhan; Treyer, Andrea; De Pascale, Martina; Hebeisen, Paul; Hamburger, Matthias; Wymann, Matthias P.
2021
Second-generation tricyclic pyrimido-pyrrolo-oxazine mTOR inhibitor with predicted blood-brain barrier permeability
RSC Medicinal Chemistry
4408248 Bohnacker, Thomas; Prota, Andrea E.; Beaufils, Florent; Burke, John E.; Melone, Anna; Inglis, Alison J.; Rageot, Denise; Sele, Alexander M.; Cmiljanovic, Vladimir; Cmiljanovic, Natasa; Bargsten, Katja; Aher, Amol; Akhmanova, Anna; Fernando Diaz, J.; Fabbro, Doriano; Zvelebil, Marketa; Williams, Roger L.; Steinmetz, Michel O.; Wymann, Matthias P.
2017
Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention
Nature communications
4408249 Beaufils, Florent; Cmiljanovic, Natasa; Cmiljanovic, Vladimir; Bohnacker, Thomas; Melone, Anna; Marone, Romina; Jackson, Eileen; Zhang, Xuxiao; Sele, Alexander; Borsari, Chiara; Mestan, Jurgen; Hebeisen, Paul; Hillmann, Petra; Giese, Bernd; Zvelebil, Marketa; Fabbro, Doriano; Williams, Roger L.; Rageot, Denise; Wymann, Matthias P.
2017
5-(4,6-Dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine (PQR309), a Potent, Brain-Penetrant, Orally Bioavailable, Pan-Class I PI3K/mTOR Inhibitor as Clinical Candidate in Oncology
Journal of Medicinal Chemistry
4408247 Breasson, Ludovic; Becattini, Barbara; Sardi, Claudia; Molinaro, Angela; Zani, Fabio; Marone, Romina; Botindari, Fabrizio; Bousquenaud, Melanie; Ruegg, Curzio; Wymann, Matthias P.; Solinas, Giovanni
2017
PI3K gamma activity in leukocytes promotes adipose tissue inflammation and early-onset insulin resistance during obesity
Science signaling
2435937 Zimmermann, Mirjam; Cal, Ruben; Janett, Elia; Hoffmann, Viktor; Bochet, Christian G.; Constable, Edwin; Beaufils, Florent; Wymann, Matthias P.
2014
Cell-Permeant and Photocleavable Chemical Inducer of Dimerization
Angewandte Chemie International Edition
2435938 Gayral, Stephanie; Garnotel, Roselyne; Castaing-Berthou, Audrey; Blaise, Sebastien; Fougerat, Anne; Berge, Elodie; Montheil, Aurelie; Malet, Nicole; Wymann, Matthias P.; Maurice, Pascal; Debelle, Laurent; Martiny, Laurent; Martinez, Laurent O.; Pshezhetsky, Alexey V.; Duca, Laurent; Laffargue, Muriel
2014
Elastin-derived peptides potentiate atherosclerosis through the immune Neu1-PI3Kγ pathway
Cardiovascular Research
4408222 Smirnova, Natalia F.; Gayral, Stephanie; Pedros, Christophe; Loirand, Gervaise; Vaillant, Nathalie; Malet, Nicole; Kassem, Sahar; Calise, Denis; Goudouneche, Dominique; Wymann, Matthias P.; Hirsch, Emilio; Gadeau, Alain-Pierre; Martinez, Laurent O.; Saoudi, Abdelhadi; Laffargue, Muriel
2014
Targeting PI3Kgamma activity decreases vascular trauma-induced intimal hyperplasia through modulation of the Th1 response
Journal of experimental medicine
2832598 Wymann, Matthias P; Simons, Kai
2013
Membrane dynamics in physiology and disease
The FEBS journal
2832595 Walser, Romy; Burke, John E; Gogvadze, Elena; Bohnacker, Thomas; Zhang, Xuxiao; Hess, Daniel; Küenzi, Peter; Leitges, Michael; Hirsch, Emilio; Williams, Roger L; Laffargue, Muriel; Wymann, Matthias P
2013
PKCβ phosphorylates PI3Kγ to activate it and release it from GPCR control
PLoS Biology
2832601 Zotes, T. M.; Arias, C. F.; Fuster, J. J.; Spada, R.; Perez-Yague, S.; Hirsch, E.; Wymann, M.; Carrera, A. C.; Andres, V.; Barber, D. F.
2013
PI3K p110γ deletion attenuates murine atherosclerosis by reducing macrophage proliferation but not polarization or apoptosis in lesions
PLoS ONE
2832585 Collmann, Emilie; Bohnacker, Thomas; Marone, Romina; Dawson, Janet; Rehberg, Markus; Stringer, Rowan; Krombach, Fritz; Burkhart, Christoph; Hirsch, Emilio; Hollingworth, Gregory J; Thomas, Matthew; Wymann, Matthias P
2013
Transient targeting of phosphoinositide 3-kinase acts as a roadblock in mast cells' route to allergy
Journal of allergy and clinical immunology
2291732 Erhart, D.; Zimmermann, M.; Jacques, O.; Wittwer, M. B.; Ernst, B.; Constable, E.; Zvelebil, M.; Beaufils, F.; Wymann, M. P.
2013
Chemical development of intracellular protein heterodimerizers
Chemistry & Biology
2832583 Barthwal, M. K.; Anzinger, J. J.; Xu, Q.; Bohnacker, T.; Wymann, M. P.; Kruth, H. S.
2013
Fluid-phase pinocytosis of native low density lipoprotein promotes murine M-CSF differentiated macrophage foam cell formation
PLoS ONE
2832594 Schmidt, C; Schneble, N; Müller, J P; Bauer, R; Perino, A; Marone, R; Rybalkin, S D; Wymann, M P; Hirsch, E; Wetzker, R
2013
Phosphoinositide 3-kinase gamma mediates microglial phagocytosis via lipid kinase-independent control of cAMP
Neuroscience
2832599 Wymann, Matthias P; Solinas, Giovanni
2013
Inhibition of phosphoinositide 3-kinase γ attenuates inflammation, obesity, and cardiovascular risk factors
Annals of the New York Academy of Sciences
1193905 Anzinger, Joshua J.; Chang, Janet; Xu, Qing; Barthwal, Manoj K.; Bohnacker, Thomas; Wymann, Matthias P.; Kruth, Howard S.
2012
Murine bone marrow-derived macrophages differentiated with GM-CSF become foam cells by PI3K?-dependent fluid-phase pinocytosis of native LDL
Journal of Lipid Research
2832587 Fougerat, A; Smirnova, N F; Gayral, S; Malet, N; Hirsch, E; Wymann, M P; Perret, B; Martinez, L O; Douillon, M; Laffargue, M
2012
Key role of PI3Kgamma in monocyte chemotactic protein-1-mediated amplification of PDGF-induced aortic smooth muscle cell migration
British journal of pharmacology
2832593 Schaefer, T; Zajonz, A; Lorentz, P; Bohnacker, T; Wymann, M P; Schweighoffer, T
2012
Luminal decoration of blood vessels by activated perivasal mast cells in allergic rhinitis
Allergy
2832591 Reichel, Christoph A; Puhr-Westerheide, Daniel; Zuchtriegel, Gabriele; Uhl, Bernd; Berberich, Nina; Zahler, Stefan; Wymann, Matthias P; Luckow, Bruno; Krombach, Fritz
2012
C-C motif chemokine CCL3 and canonical neutrophil attractants promote neutrophil extravasation through common and distinct mechanisms
Blood
1195815 Wymann, Matthias
2012
PI3Ks-drug targets in inflammation and cancer
Subcellular biochemistry
Showing records 1 - 20 (of 50)
