|
ID
|
Author
|
Year
|
Title
|
Publisher
|
| 4645745 |
Duthaler, Urs; Bachmann, Fabio; Suenderhauf, Claudia; Grandinetti, Tanja; Pfefferkorn, Florian; Haschke, Manuel; Hruz, Petr; Bouitbir, Jamal; Krähenbühl, Stephan |
2022 |
Liver Cirrhosis Affects the Pharmacokinetics of the Six Substrates of the Basel Phenotyping Cocktail Differently. |
Clinical pharmacokinetics |
| 4627070 |
Bachmann, Fabio; Meyer Zu Schwabedissen, Henriette E; Duthaler, Urs; Krähenbühl, Stephan |
2022 |
Cytochrome P450 1A2 is the most important enzyme for hepatic metabolism of the metamizole metabolite 4-methylaminoantipyrine. |
British journal of clinical pharmacology |
| 4661956 |
Novakova, Katerina; Török, Michael; Panajatovic, Miljenko; Bouitbir, Jamal; Duong, François H T; Handschin, Christoph; Krähenbühl, Stephan |
2022 |
PGC-1α and MEF2 Regulate the Transcription of the Carnitine Transporter OCTN2 Gene in C2C12 Cells and in Mouse Skeletal Muscle. |
International journal of molecular sciences |
| 4641928 |
Roos, Noëmi Johanna; Mancuso, Riccardo Vincenzo; Sanvee, Gerda Mawududzi; Bouitbir, Jamal; Krähenbühl, Stephan |
2022 |
Imatinib disturbs lysosomal function and morphology and impairs the activity of mTORC1 in human hepatocyte cell lines |
Food and Chemical Toxicology |
| 4642055 |
Bouitbir, Jamal; Panajatovic, Miljenko V.; Krähenbühl, Stephan |
2022 |
Mitochondrial Toxicity Associated with Imatinib and Sorafenib in Isolated Rat Heart Fibers and the Cardiomyoblast H9c2 Cell Line |
International journal of molecular sciences |
| 4641929 |
Blaser, Lea S.; Duthaler, Urs; Bouitbir, Jamal; Leuppi-Taegtmeyer, Anne B.; Liakoni, Evangelia; Dolf, Reto; Mayr, Michael; Drewe, Jürgen; Krähenbühl, Stephan; Haschke, Manuel |
2021 |
Comparative Effects of Metamizole (Dipyrone) and Naproxen on Renal Function and Prostacyclin Synthesis in Salt-Depleted Healthy Subjects - A Randomized Controlled Parallel Group Study |
Frontiers in Pharmacology |
| 4618035 |
Schittny, Andreas; Waldner, Samuel; Duthaler, Urs; Vorobyev, Alexander; Abramovich, Rimma; Krähenbühl, Stephan; Puchkov, Maxim; Huwyler, Jörg |
2021 |
Particle Forming Amorphous Solid Dispersions: A Mechanistic Randomized Pharmacokinetic Study in Humans |
pharmaceutics |
| 4618955 |
Witzigmann, Dominik; Grossen, Philip; Quintavalle, Cristina; Lanzafame, Manuela; Schenk, Susanne H.; Tran, Xue-Ting; Englinger, Bernhard; Hauswirth, Patrick; Grünig, David; van Schoonhoven, Sushilla; Krähenbühl, Stephan; Terracciano, Luigi M.; Berger, Walter; Piscuoglio, Salvatore; Quagliata, Luca; Rommelaere, Jean; Nüesch, Jürg P. F.; Huwyler, Jörg |
2021 |
Non-viral gene delivery of the oncotoxic protein NS1 for treatment of hepatocellular carcinoma |
Journal of Controlled Release |
| 4615202 |
Bachmann, Fabio; Duthaler, Urs; Meyer Zu Schwabedissen, Henriette E.; Puchkov, Maxim; Huwyler, Jörg; Haschke, Manuel; Krähenbühl, Stephan |
2021 |
Metamizole is a Moderate Cytochrome P450 Inducer Via the Constitutive Androstane Receptor and a Weak Inhibitor of CYP1A2 |
Clinical Pharmacology and Therapeutics |
| 4620421 |
Panajatovic, Miljenko V.; Singh, Francois; Krähenbühl, Stephan; Bouitbir, Jamal |
2021 |
Effects of Simvastatin on Lipid Metabolism in Wild-Type Mice and Mice with Muscle PGC-1α Overexpression |
International Journal of Molecular Siences |
| 4625743 |
Sanvee, Gerda M; Hitzfeld, Leonie; Bouitbir, Jamal; Krähenbühl, Stephan |
2021 |
mTORC2 is an important target for simvastatin-associated toxicity in C2C12 cells and mouse skeletal muscle - Roles of Rap1 geranylgeranylation and mitochondrial dysfunction. |
Biochemical pharmacology |
| 4625744 |
Sanvee, Gerda M; Bouitbir, Jamal; Krähenbühl, Stephan |
2021 |
C2C12 myoblasts are more sensitive to the toxic effects of simvastatin than myotubes and show impaired proliferation and myotube formation. |
Biochemical pharmacology |
| 4602364 |
Bouitbir, Jamal; Alshaikhali, Abdallah; Panajatovic, Miljenko V.; Abegg, Vanessa F.; Paech, Franziska; Krähenbühl, Stephan |
2020 |
Mechanisms of Cardiotoxicity Associated with Tyrosine Kinase Inhibitors in H9c2 Cells and Mice |
European cardiology |
| 4602363 |
Panajatovic, Miljenko V.; Singh, François; Duthaler, Urs; Krähenbühl, Stephan; Bouitbir, Jamal |
2020 |
Role of PGC-1-alpha-associated Mitochondrial Biogenesis in Statin-induced Myotoxicity |
European cardiology |
| 4602362 |
Sanvee, G. M.; Panajatovic, M.; Bouitbir, D. J.; Krähenbühl, Dmdps |
2020 |
Statins and Insulin Resistance |
European cardiology |
| 4602365 |
Zhou, Xun; Bouitbir, Jamal; Liechti, Matthias E.; Krähenbühl, Stephan; Mancuso, Riccardo V. |
2020 |
Para; -Halogenation of Amphetamine and Methcathinone Increases the Mitochondrial Toxicity in Undifferentiated and Differentiated SH-SY5Y Cells |
International journal of molecular sciences |
| 4602366 |
Zhou, Xun; Bouitbir, Jamal; Liechti, Matthias E.; Krähenbühl, Stephan; Mancuso, Riccardo V. |
2020 |
Hyperthermia Increases Neurotoxicity Associated with Novel Methcathinones |
Cells |
| 4602361 |
Rudin, Deborah; Schmutz, Maurice; Roos, Noëmi Johanna; Bouitbir, Jamal; Krähenbühl, Stephan |
2020 |
Reactive Metamizole Metabolites Enhance the Toxicity of Hemin on the ATP Pool in HL60 Cells by Inhibition of Glycolysis |
Biomedicines |
| 4604806 |
Panajatovic, Miljenko Valentin; Singh, François; Krähenbühl, Stephan; Bouitbir, Jamal |
2020 |
Simvastatin Impairs Glucose Homeostasis in Mice Depending on PGC-1α Skeletal Muscle Expression |
Biomedicines |
| 4602367 |
Panajatovic, Miljenko Valentin; Singh, François; Roos, Noëmi Johanna; Duthaler, Urs; Handschin, Christoph; Krähenbühl, Stephan; Bouitbir, Jamal |
2020 |
PGC-1α plays a pivotal role in simvastatin-induced exercise impairment in mice |
Acta physiologica (Oxford, England) |
